Lipoproteins (Lipids + Proteins)

• Globular micelle-like particles.
• Consists of the non-polar core of tri glycerols and cholesteryl esters,
• The protein part of lipoprotein is called apolipoprotein and acts as cellular targeting signals.

Classes of lipoprotein

a) Chylomicrons:

• Transport dietary glyceride and cholesterol from the intestine to the tissue.

b) VLDL:

• Transport glyceride from the liver to tissue.

c) LDL:

• Delivers cholesterol to the cells.

d) IDL:

• Pick up cholesterol from HDL to become LDL.

e) HDL:

• Delivers cholesterol to the liver.

Note:

• Intestinal mucosal cells convert dietary FA to triacylglycerol and package them.
• Particles are released to intestinal lymph.
• Transported through lymphatic vessels.
• Blood stream then delivers chylomicrons throughout the body.