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Biochemistry and molecular logic of life
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Learn General Biochemistry with Rahul
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Reactions promoted by radiation

  • UV light induces the condensation of two ethylene groups to form a cyclobutene ring.

 

i.e. Adjacent pyrimidine –radiation– à cyclobutene pyrimidine dimers.

  • Ionization radiations can cause ring openings and fragmentation of bases.

 

Note: DNA –Replication – DNA

          DNA — Transcription — RNA – Translation —Protein

  • Alkylating agents can alter certain bases of DNA.
  • Dimethyl sulfate can methylate a guanine to yield O6-methylguanine which can’t base pair with cytosine.
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